We provide OTB Applications for Windows Seven and later through standalone packages. They are cross-compiled with MinGW, for 32bit and 64bit platforms. They contain all OTB Applications and their launchers (both command line and graphical launchers are provided). Check the download page : OTB Download page
There is a 32bit and a 64bit version. They contain the same directory structure:
The applications can be launched from the Mapla launcher. If you want to use the otbcli and otbgui launchers, you can initialize a command prompt with otbenv.bat.